Universitat Internacional de Catalunya - BarcelonaMicrobiology and Immunology
Module: Basic biomedical sciences relevant in dentistry
Matter: Microbiology and Immunology (Biology)
Main language of instruction: Spanish
Other languages of instruction: Catalan, English
If the student is enrolled for the English track then classes for that subject will be taught in the same language and also in Catalan.
Head instructor
Dra. Andrea Natalia RICCO - anricco@uic.es
Office hours
Questions will be answered in person with the involved instructor. Questions will not be answered by mail.
To make an appointment:
Microbiology:
Jordi Mas (jmas@uic.es)
Immunology
Natalia Ricco (anricco@uic.es)
Microbiology and immunology, from the point of view of a health professional,are two sides of the same coin. The first is dedicated to the study of a broad group of living organisms with which we coexist and establish different degrees of interactions. In addition to economic reasons, we will focus in the ability of many microorganisms to cause diseases in humans. The immunology, on the other hand, deals with the mechanisms disposed by the human body to protect against the infections caused by, among others, the microorganisms.
Students must have a previous knowledge in biochemistry, human genetics, molecular biology, cellular biology. The student`s access route assures the basic knowledge needed to follow the present subject.
The first goal of this subject is to provide the student with knowledge about the characteristics and peculiarities of a broad variety of organisms with which we establish a number of steady interactions as well as the benefits and damages that can be determined by then. Special interest will of course be given to oral microbiology.
As important as the former goal is to provide structural and functional overview of the immune system, both in health and disease conditions, again focusing in the special immunological characteristics of the mouth and the oral cavity.
The last goal of this subject is to show the student the most relevant techniques and processes employed in this scientific fields in order to provide a critical capacity useful for the latter professional career.
Knowledge and understanding of the microbiotic world in terms of existence, history diversity and characteristics.
Knowledge of the most common infectious diseases determined by the different types of microorganisms.
Knowledge on the different tools for control of microorganisms' growth and the infections determined by then.
Knowledge of the economical and scientific relevance of microorganisms
Knowledge of the basic techniques on how to handle and interpret microbiological data
Knowledge on the structure and function of the immune system both in health and disease conditions
Knowledge on the transfer to the human healthcare of the advances in the field of the immunology.
Dysfunction of the immune system
Interpretation of the clinical information related to the immune system.
Knowledge of scientific vocabulary in English and Spanish in the field of Immunology
Immunology
Unit 1. Description of the immune system: Immune system the sixth sense, structure and function of the immune system: organs, cells and molecules.
Unit 2. The innate part of the immune system: the complement system, the macrophage
Unit 3. The adaptive part of the immune system: antigens and antigen presentation, the MHC / HLA system
Unit 4. The adaptive part of the immune system: T and B lymphocyte, diversity in the immune system
Unit 5. The immune system in action: immunity against microorganisms, immunity against tumors.
Unit 6. The immune system in action: immunity from transplants, vaccines.
Unit 7. Dysfunctions of the immune system: immune tolerance, immunodeficiencies.
Unit 8. Dysfunctions of the immune system: autoimmunity, hypersensitivity
Unit 9. Immunological techniques: poly / monoclonal antibodies, flow cytometry, ELISA, cell cultures, cell lines.
Microbiology
Unit 1. Introduction to Microbiology: definition and overview, brief history, key figures, oral microbiology today.
Unit 2. I Analysis and microbiological diagnosis (laboratory techniques): standard microbiological practices, antigen detection, identification of microorganisms, technical-omics (genomics, proteomics ...)
Unit 3. Laboratory techniques: control of microbial growth, sterilisation.
Unit 4. Morphology and bacterial surface structures: cytoplasmic membrane wall bacterial outer membrane of Gram negative bacteria, capsule
Unit 5. Bacterial appendices, extracellular products and intracellular structures: mobility flagella, fimbriae and pili, toxins, bacterial spores, organelles of eukaryotic microorganisms
Unit 6. Bacterial metabolism: an overview of bacterial metabolism, energy generation pathways, culture media, main metabolic characteristics of oral bacteria
Unit 7. Specific microbial genetics: generation of genetic variability, conjugation, transposition, transformation. Genome projects.
Unit 8. Virology: general characteristics of viruses and viral replication, virus quantification
Unit 9. Main families of viruses: bacteriophage and human pathogenic viruses
Unit 10. Health microbiology: microbial pathogenicity, microorganism-person relationship, transmission of microorganisms.
Unit 11. Introduction to bacterial taxonomy: bacterial species concept, classification of bacteria
Unit 12. Major families of bacteria: taxonomic characteristics of oral bacteria
Unit 13. Microbial diversity: fungi and parasites oral Interest
Unit 14. Oral Microbiology of dental plaque, caries.
Unit 15. Periodontal, endodontic and peri-implant microbiology and processes.
Problem based learning:
Vaccines: flu, AIDS, malaria
Transplants immunology
Immunology during pregnancy
Viral infections I
Viral infections II
Bacterial infections I
Bacterial infections II
Eukaryotic infections
Basic Immunology: Functions and Disorders of the Immune System A.K. Abbas, A.H. Lichtman, S. Pillai. Elsevier Ed. 4ª ed. 2014
Inmunobiología: el sistema inmunitario en condiciones de salud y de enfermedad. Janeway et al. Ed. Masson 7ª ed. 2009.
Microbiología Estomatológica: Fundamentos y guía práctica (3ª edición). Marta Negroni. Ed Médica. Panamericana
Brock. Microbiología de los microorganismos. M.T. Madigan, J.M. Martinko y J. Parker. 10ª Ed. Prentice Hall.1999.
Microbiología. Prescott, Harley y Klein. McGraw-Hill 7ª Ed, 2008.
Microbiología Médica. P.R. Murray, K.S. Rosenthal y M.A. Pfaller. 7ª Ed. Elsevier Science. 2013
Sherris. Microbiología Médica. Una introducción a las Enfermedades Infecciosas. K.J. Ryan y C.G. Ray editores. 4ª Ed. McGraw-Hill Interamericana. 2004.