Universitat Internacional de Catalunya - BarcelonaBody Structure and Function: Blood and Immune System
Module: Morfología, estructura y función del cuerpo humano
Matter: Estructura y función: sangre y sistema inmunitario
Main language of instruction: Spanish
Head instructor
Dr. Javier JIMÉNEZ - jjimenez@uic.es
Office hours
Responsable: Javier Jiménez (jjimenez@uic.es)
Practical courses:
Immunology:Helena Muley (elenamuley@uic.es)
Blood physiology:
Case methods:
Bood physiology: Ramon Salinas (rsalinas@bst.cat)
Immunology: Eva Quandt (equandt@uic.es)
Histology: Noelia Pérez (nperez@uic.es)
Attention: jjimenez@uic.es
Two large pieces of knowledge are grouped under the name “Blood Physiology and Immune system”. In one hand the study of the blood from the point of view of the physiology, providing a description of all its components, the function and the relevance for the human being. In the other hand, the immunology, (mechanisms displayed for our body to get defended or to interact with eventual infections or malfunction of some of our cells). Both systems bears an special interest for sanitary students so the idea of this subject focus on provide to the student knowledge related to them not only in both health and disease situations, but also the human health incidence determined by the development of the blood and immune system knowledge .
We consider indispensable to have a previous knowledge in biochemistry, human genetics, molecular biology, cellular biology. All these subjects have been scheduled before in the medicine studies.
Provide basic ideas on the blood anatomy and function
Provide a description of the immune system both from a structural and functional point of view either in health and disease conditions.
Provide the idea of the homeostatic role played by both systems and it essentiality in the right functioning of the body.
Understand the relevance in terms of human health determined by the development in the understanding of the blood and the immune system.
Once attended the subject, the student will have a broad view over the components of the blood ant it functioning both in the homeostatic role and in the role of container of the immune system. The student will obtain a whole vision of the blood and immune system both in health and disease conditions. Finally, the student will be able to know, analyse and interpret the data coming from the different techniques in the science fields.
Comprehensive knowledge of the blood and its components.
Knowledge of the blood function and specifically of the immune system.
Transfer to the human health of the knowledge accumulated on the immune system.
Blood diseases and immune disorders
Interpretation of clinical data related to the blood and immune system
Knowledge of the different tools for the study of the blood and the immune system.
Blood Physiology
Theme 1. Blood physiology and hemostasis
Theme 2 Hematopoiesis
Theme 3. The erythrocyte
Blood and immune system histology
Theme 1. Peripheral blood. Erythrocytes. Platelets.
Theme 2. Peripheral blood. Leukocytes: neutrophils, eosinophils, basophils, lymphocytes, monocytes.
Theme 3. I. Bone marrow and hematopoiesis Microscopic structure. Sinusoids. Supporting cells. Hematopoiesis. Erythropoiesis.
Theme 4. Hematopoiesis II. Granulopoiesis. Lymphopoiesis. Monopoyesis. Thrombopoiesis.
Theme 5. Lymphoid Tissues. Lymph node. Microscopic Structure: Capsule, sinuses, cortex and medulla. Lymphoid follicles.
Theme 6. Sifuso lymphoid tissue and nodular. Mucosa-associated lymphoid tissue (MALT). Tonsils. Cecal appendix. Peyer's patches.
Theme 7. Timo. Microscopic structure: cortex and medulla. Epithelial and lymphoid cells.
Theme 8. Spleen. Microscopic structure: white pulp. Red pulp. Splenic blood circulation.
Immunology for physicians
Theme 1. Immune system description: the immune system, the sixth sense, structure and function of the immune system: organs, cells, molecules.
Theme 2. The innate part of the immune system: the complement system, the macrophage.
Theme 3. The adaptive part of the immune system: antigens, antigen-presentation, the MCH/HLA system, the T and B lymphocyte, generation of diversity in the immune system.
Theme 4. The immune system in action: immunity against microorganisms, tumours, transplants, vaccines
Theme 5. Immune system dysfunctions: immune tolerance, immunodeficiency, autoimmunity, hypersensitivity
Theme 6. Immunological techniques: antibodies poli/monoclonals, flow cytometry, ELISA, cell lines, cellular cultures.
Problem based learning:
Vaccines: flu, AIDS, malaria
Transplants immunology
Immunology during the pregnancy
Inmunobiología de Janeway. Janeway et al. Ed. Mc Graw Hill 7ª ed. 2009.
Inmunología. Doan T, Melvold R, Viselli S, Waltenbaugh . Ed. Wolkers Kluwer. 2008.
Inmunología. Biología y patología del sistema inmunitario. Regueiro, López-Larrea. 4ª ed revisada. Ed. Panamericana 2011
Inmunología básica, funciones y transtornos del sistema inmunitario. Abul K abbas. cuarta edición 2014. Elsevier Saunders