Universitat Internacional de Catalunya - BarcelonaHematology
Main language of instruction: Spanish
Head instructor
Dr. Ramón SALINAS - rsalinas@uic.es
Office hours
Ramon Salinas Argente
correo electronic: rsalinas@bst.cat
PARCIAL 19/11/2018
Haematology is a medical discipline in itself, which involves diagnosing and treating patients with haematological diseases, and also provides support to other medical and surgical specialties (blood counts, haemostasis, haematological cytology, molecular haematology and transfusion medicine).
The lecturers of the haematology course do not have the intention of training haematologists, but to provide students with the knowledge of haematology needed to practise medicine. This is their contribution towards achieving the final goal of the degree: training doctors in all technical and human aspects.
However, the lecturers’ ambition goes a little further: we wish to pass on to students our enthusiasm for this specialty, which is sometimes wonderful and sometimes terribly cruel. We hope that students will learn something about haematology, and also acquire an interest in learning more about it throughout their professional career.
To have passed the subject: "Structure and function of the blood and immune system".
The haematology training course aims to provide students with specific tools that will help them understand the main problems associated with haematological diseases.
The student should also be able to identify blood disorders secondary to other medical problems.
Additionally, the optimal diagnostic processes to guide diagnosis will be established, using available diagnostic tests and taking into consideration cost-effectiveness variables.
The treatment bases of haematology and side effects will also be presented.
Finally, students will reflect on the human problems resulting from haematological diseases and be provided with tools to cope with them psychologically and communicatively.
At the end of the learning process the student should be able to:
Detect abnormal blood count tests and basic haemostasis
Guide the diagnosis of anaemia and be able to treat the most prevalent types
Differentiate polycythaemia vera from secondary poliglobulias
Know the methodology to differentiate between reactive leukocytosis lymphocytic and myeloproliferative neoplasia
Identify agranulocytosis and its causes
Know the preventive measures to be taken in a neutropenic patient
Identify the characteristics of essential thrombocythaemia and learn to distinguish it from reactive thrombocytosis
Guide the diagnosis of idiopathic thrombocytopenic purpura and start the treatment protocol and bleeding preventive measures
Understand the concepts of bicytopenia and pancytopenia and their causes, and guide diagnosis
Know the aetiology, pathophysiology, diagnosis and treatment of major haematological diseases
Know how to examine lymphadenopathy and splenomegaly, recognise the warning signs and know the diagnostic process
Ability to clinically and analytically treat of haemorrhagic syndrome
Know the conditions that predispose thrombosis, the pathologies that cause thrombophilia, preventive measures to be taken and commonly used anticoagulant treatments
Understand the technical characteristics, indications and usefulness of bone marrow cytology, bone marrow biopsy and lymph node biopsy
Acquire basic knowledge of highly complex diagnostic techniques (immunophenotype, cytogenetics, molecular biology) and understand the logic of their application in haematological diagnosis
Develop a psychological approach to patients and their families, using effective communication tools, individualized for each patient
Understand the theoretical basis of pre-transfusion screening and know how to identify and respond to a transfusion reaction
Incorporate the use of cytostatics, hematopoietic colony stimulating factors, biological response modifiers, differentiation inducers and radiotherapy as tools in the treatment of haematological diseases
Understand the basics of bone marrow transplantation, differentiation of types and indications
Lectures: each lecture lasts for two hours, is for the whole group and is given once.
Anaemia (3 hours). Concept and classification. Acute post-haemorrhagic anaemia, iron deficiency, associated with chronic diseases, sideroblastic, congenital dyserythropoietic, megaloblastic. Congenital and acquired haemolytic anaemia.
Bone marrow deficiencies and diseases of the leukocyte system: (2 hours). Aplastic anaemia, bone marrow failure selective neutropenia, genetic defects and disorders of granulocytes functionalism.
Myelodysplastic syndromes (1 hour). Concept, aetiology, epidemiology, pathogenesis, classification and nomenclature. Clinical picture, diagnosis, differential diagnosis, prognosis and treatment.
Acute leukaemia (3 hours). General, acute lymphoblastic leukaemia, acute myeloid leukaemia, treatment
Chronic myeloproliferative syndromes and mastocytosis (3 hours). General, chronic myeloid leukaemia, polycythaemia vera, essential thrombocythaemia, primary myelofibrosis, mastocytosis.
Lymphomas and lymphoproliferative disorders. Histiocytosis (4 hours). Pathology of lymphomas, lymphoproliferative disorders, Hodgkin’s lymphoma, non-Hodgkin’s lymphoma, B and T lymphomas associated with immunodeficiency, other glandular pathologies.
Monoclonal gammopathies - Multiple myeloma (2 hours). Monoclonal gammopathy of undetermined significance, multiple myeloma, Waldenstrom's macroglobulinaemia, heavy chain disease. Primary amyloidosis.
Platelet disorders and coagulopathies (3 hours). Semiology and exploration of haemostasis, angiopathic purpura, thrombocytopenia, thrombocytopathies, congenital and acquired coagulation disorders.
Thrombosis and thrombophilia (2 hours). Thrombosis, thrombophilia. Antithrombotic prophylaxis and treatment.
Transfusion medicine (1 hour). Standard procedures in pre-transfusion screening. Indications for transfusion of packed red blood cells, platelets and plasma.
Progenitor cell transplantation (1 hour)
Case studies: Two clinical cases wiill be presented. Each session is for 50% of the group.
Problem-based learning: Each PBL session will include two clinical problems in two hours. Each session is for 50% of the group.
Laboratory Skills. Two hours. Each session is for 20% of the group. Five sessions.
There will be three classes of two hours each covering the simulation (using robotic mannequins and use of specific materials) of three cases with typical haematological diseases.
| METHODOLOGY | COMPETENCES |
|---|---|
| 09 15 16 17 18 19 21 26 |
The syllabus of the course will be based on the relevant haematology sections of two textbooks:
Farreras - Rozman: Internal Medicine. Elsevier
Harrison. Principles of Internal Medicine. McGraw Hill
Sanz MA, Carreras E; Manual practico de hematologia clinica. Ed Antares
This content is considered examination material, whether or not it has been covered in lectures.
Teachers may provide students with additional material for the classes they teach, in addition. Any of these materials and any point discussed in class can be included in the examination.
E: exam date | R: revision date | 1: first session | 2: second session: