Universitat Internacional de Catalunya - BarcelonaBody Structure and Function: Gastrointestinal System and Metabolism
Main language of instruction: Spanish
Head instructor
Dr. Pau MEZQUITA - pmezquita@uic.es
Office hours
Anatomy / Radiologic anatomy: Dr. Michel Zabalza (mzabalza@uic.es) / Dra. Paloma Puyalto (ppuyalto@uic.es)
Histology: Dr. Napoleón de la Ossa (ndelaossa@uic.es)
Physiology: Dr. Pau Mezquita (pmezquita@uic.es)
Metabolism: Dr. Sara Hernández (shernandez@uic.es), Dr. Helena Muley (helenamuley@uic.es)
None
After completing the course students will be able to:
I. ANATOMY OF THE DIGESTIVE SYSTEM.
1. Abdomen and pelvis.
2. Mouth, pharynx, esophagus, stomach, small intestine, colon and rectum.
3. Liver.
4. Pancreas.
II. HISTOLOGY OF THE DIGESTIVE SYSTEM
1. Mouth and Salivary Glands.
1.1 Microscopic structure of the oral mucosa.
1.2 Microscopic structure of the language.
1.3 Microscopic structure of the salivary glands and excretory secretory portion.
2. Esophagus and Stomach.
2.1 Microscopic structure of the esophagus: Layers of the esophagus. Gastroesophageal junction.
2.2 Microscopic structure of the stomach: Layers stomach. Types of gastric mucosa. Gastric cells types.
3. Small intestine and large intestine.
3.1 Microscopic structure of the small intestine mucosa types and cell types.
3.2 Microscopic structure of the large intestine: Types of mucosa and cell types of the colon and rectum. Anal canal.
4. Liver and Pancreas.
4.1 Microscopic structure of the liver: Type of cells and histological structures.
4.2 Microscopic structure of the exocrine pancreas: Types of cells and histological structures.
III. PHYSIOLOGY OF THE DIGESTIVE SYSTEM
1. Motor activities.
1.1 Functions of the digestive tract.
1.2 Chewing, swallowing and esophageal transit.
1.3 Motor activity of the stomach.
1.4 Small intestinal motor activity.
1.5 Motor activity of the colon.
1.6. Vomiting
2. Secreting digestive activities.
2.1 Salivary secretion.
2.2 Gastric secretion.
2.3 Pancreatic secretion.
2.4 Biliary secretion.
2.5 Intestinal secretion.
3. Digestion and absorption.
3.1 Digestion and absorption of carbohydrates.
3.2 Protein digestion and absorption of peptides and amino acids.
3.3 Digestion and absorption of lipids.
3.4 Absorption of water and electrolytes.
3.5 Intestinal absorption of Ca2 +.
3.6 Intestinal absorption of Fe2 +.
3.7 Intestinal absorption of vitamins.
4. Functions of the liver.
4.1 Functions of hepatocytes.
4.2 Storage Features liver.
4.3 Functions of endothelial cells, Kupffer cells, stellate cells and cholangiocytes.
IV. METABOLISM
1. Energetic Metabolism Review
Metabolism of sugars and lipids. Energy balance. Hormonal control of energy balance. Hormonal control of hunger. Situations lack of energy sources.
2. Metabolism of cholesterol and special lipids.
Absorption and distribution of cholesterol. Products derived from cholesterol. Products derived from phospholipids.
3. Protein Metabolism.
Role of transaminases in removing nitrogen groups. Urea cycle. Oxidation of carbon backbone. Processing pathways of amino acids. Main pathologies of amino acid metabolism.
4. Nucleotide metabolism.
Synthetic routes i dels nucleotide degradation. Accumulation of uric acid.
5. Clinical biochemistry.
Measuring systems in current clinical biochemistry. Reliability and standards. Required parameters.
G. Tortora. Principios de Anatomía y fisiología, 11a ed. Panamericana (2006).
Drake, R.L. et a. Gray Anatomía para estudiantes, 2a ed. Elsevier (2010).
Shünke M. et al. Prometheus (tomo 2), 2a ed. Panamericana (2010).
A. Stevens. Histología humana, 3a ed. Elsevier (2006).
A.L. Kierszenbaum. Histología y Biología celular, 2a ed. Elsevier (2008).
E.N. Marieb. Human Anatomy and Physiology, 7th ed. Pearson Int. Ed. (2007).
Mezquita. Fisiología médica, 1a ed. Panamericana (2011).
L.S. Costanzo. Fisiología, 4a ed. Elsevier (2011).
Champe. Bioquímica. 3a ed. Wolters Kluwer.