ALDEA MALO, Martí
Departament
Departamento de Ciencias Básicas de Ciencias de la SaludPerfil profesor
Professor Agregat o Titular
Departament de Ciències Bàsiques. Universitat Internacional de Catalunya
Formación Académica
- Otros. Universitat Autònoma de Barcelona
Articles
- Moreno, D.; Jenkis, K.; Morlot, S.; Charvin, G.; Csikasz-Nagy, A.; Aldea, M., (2019), "Proteostasis collapse, a hallmark of aging, hinders the chaperone-Start network and arrests cells in G1", eLife, vol.8, ISSN: 2050-084X.
- Moreno, D.; Parisi, E.; Yahya, G.; Vaggi, F.; Csikász, A.; Aldea, M., (2019), "Competition in the chaperone-client network subordinates cell-cycle entry to growth and stress", Life Science Alliance, vol.2, No.2, ISSN: 2575-1077.
- Moreno, D.; Aldea, M., (2019), "Coincidence analysis of molecular dynamics by raster image correlation spectroscopy", Methods in Molecular Biology, vol.2040, pp. 375-384, ISSN: 1940-6029 10643745.
- Parisi, E.; Yahya, G.; Flores, A.; Aldea, M., (2018), "Cdc48/p97 segregase is modulated by cyclin-dependent kinase to determine cyclin fate during G1 progression", Embo journal, vol.37, No.16, ISSN: 0261-4189.
- Martínez-Laínez, JM.; Moreno, D.; Parisi, E.; Clotet, J.; Aldea, M., (2018), "Centromeric signaling proteins boost G1 cyclin degradation and modulate cell size in budding yeast", PLOS biology, vol.16, No.8, ISSN: 1544-9173.
- Aldea, M.; Jenkins, K.; Csikász, A., (2017), "Growth Rate as a Direct Regulator of the Start Network to Set Cell Size", Frontiers in cell and developmental biology, vol.5, pp. 57-62, ISSN: 2296-634X.
- Aldea, M., (2017), "Compartmentalization of ER-bound chaperone confines protein deposit formation to the aging yeast cell", Current biology, vol.27, pp. 773-783, ISSN: 0960-9822.
- Deniz, Ö.; Flores, Ó.; Aldea, M.; Soler-López, M.; Orozco, M., (2016), "Nucleosome architecture throughout the cell cycle", Scientific Reports, vol.6, No.19729, pp. 1-11, ISSN: 2045-2322.
- Georgieva, M.V.; Yahya, G.; Codó, L.; Ortíz, R.; Gallego, C.; Orozco, M.; Aldea, M., (2015), "Inntags: small self-structured epitopes for innocuous protein tagging", Nature methods, vol.12, No.10, pp. 955-958, ISSN: 1548-7091.
- Yahya, G.; Parisi, E.; Flores, A.; Gallego, C.; Aldea, M., (2014), "A Whi7-anchored loop controls de G1 Cdk-cyclin complex at Start.", Molecular cell, vol.53, pp. 115-126, ISSN: 1097-2765.
- Menoyo, S.; Ricco, N.; Bru, S.; Hernández-Ortega, S; Escoté, X.; Aldea, M.; Clotet, J., (2013), "Phosphate-Activated Cyclin-Dependent Kinase Stabilizes G(1) Cyclin To Trigger Cell Cycle Entry", Mol Cell Biol., vol.33(7), pp. 1273-1284, ISSN: 1098-5549.
- Ferrezuelo, F.; Colomina, N.; Palmisano, A.; Garí, E.; Gallego, C.; Csikasz-Nagy, A.; Aldea, M., (2012), "The critical size is set at a single-cell level by growth rate to attain homeostasis and adaptation", Nature communications, vol.3, No.1012, pp. 1-11, ISSN: 2041-1723.
- Ferrezuelo, F.; Colomina, N.; Futcher, B.; Aldea, M., (2010), "The transcriptional network activated by Cln3 cyclin at the G1-to-S transition of the yeast cell cycle", Genome biology, vol.11, No.6, pp. 1-9, ISSN: 1474-760X.
- Vergés, E.; Colomina, N.; Garí, E.; Gallego, C.; Aldea, M., (2007), "Cyclin Cln3 is retained at the ER and released by the J chaperone Ydj1 in late G1 to trigger cell cycle entry", Molecular cell, vol.26, No.5, pp. 649-662, ISSN: 1097-2765.
- Clotet, J.; Escoté, X.; Adrover, MÀ; Yaakov, G.; Garí, E.; Aldea, M.; De Nadal, E.; Posas, F., (2006), "Phosphorylation of Hsl1 by Hog1 leads to a G2 arrest essential for cell survival at high osmolarity.", Embo journal, vol.25, pp. 2338-2346, ISSN: 0261-4189.
- Clotet, J.; Garí, E.; Aldea, M.; Ariño, J., (1999), "The yeast Ser/Thr phosphatases SIT4 and PPZ1 play opposite roles in the regulation of the cell cycle.", Molecular and cellular biology, vol.19, pp. 2408-2415, ISSN: 0270-7306.
Proyectos de investigación
Proteotoxic aggregates, chaperome alterations and cell proliferation decline during cell aging
IP: Aldea, M.
MINE - MINECO. Ministerio de Economía y Competitividad
30/12/2016 - 29/12/2019
Prions and aggregons as inhibitors of Start: a path to cell ageing.
IP: Aldea, M.
MINE - MINECO. Ministerio de Economía y Competitividad
01/01/2014 - 31/12/2016
Actividades
Federation of European Biochemical Societies Congress
Ponència convidada "Growth sensors in the Start network to set cell size", 2017.
