GELLA CONCUSTELL, Alejandro

Departament
Departament de Ciències Bàsiques de Ciències de la Salut
Grup de recerca
Investigació en Neurociències

Formació acadèmica

  • Bioquímica. Universidad Autónoma de Barcelona, 2006
  • Avances en Biología Molecular. Universidad de Barcelona, 2009
  • Ciencias Químicas. Universidad de Barcelona, 2001

Articles

  • Palomo-Guerrero, M.; Cosgaya, J.; Gella, A.; Casals, N; Grijota-Martinez,C., (2018), "Uridine-5'-triphosphate partially partially blocks differentiation signals and favors a more repair state in cultured rat Schwann cells", Neuroscience, ISSN: 0306-4522.
  • Segura, M.; Pedreno, C.; Obiols, J.; Taurines, R.; Pamias, M.; Gruenblatt, E.; Gella, A., (2015), "Neurotrophin blood-based gene expression and social cognition analysis in patients with autism spectrum disorder", Neurogenetics, vol.16, No.2, pp. 123-131, ISSN: 1364-6745.
  • Lamarca, A.; Gella, A.; Martiañez, T.; Segura, M.; Figueiro, J.; Grijota-Martinez,C.; Trullas, R.; Casals, N, (2014), "Uridine 5'-triphosphate promotes in vitro Schwannoma cell migration through matrix metalloproteinase-2 activation", PLoS One, vol.9, No.6, ISSN: 1932-6203.
  • Martiáñez, T.; Lamarca, A.; Casals, N; Gella, A., (2013), "N-cadherin expression is regulated by UTP in schwannoma cells", Purinergic Signalling, vol.9, pp. 259-270, ISSN: 1573-9538.
  • Gella, A., (2012), "UTP affects the schwannoma cell line proteome through P2Y receptors leading to cytoskeletal reorganization", Proteomics, vol.12(1), pp. 145-156, ISSN: 1615-9853.
  • Gella, A.; Martiañez, T.; Lamarca, A.; Gutierrez, C.; Durany, N.; Casals, N, (2011), "A Nucleotide-Based Drug Protects against Glutamate- and MPP+-Induced Neurotoxicity", Neuroscience and Medicine, vol.2, pp. 154-160.
  • Gella, A., (2011), "Dense Shell Glycodendrimers as Potential Non-toxic Antiamyloidogenic Agents in Alzheimer's Disease. Amyloid-Dendrimer Aggregates Morphology and Cell Toxicity.", Biomacromolecules, vol.12(11), pp. 3903-3909, ISSN: 1525-7797.
  • Gella, A., (2011), "Is Ankyrin a genetic risk factor for psychiatric phenotypes?", BMC psychiatry, vol.11, pp. 103-107, ISSN: 1471-244X.
  • Gella, A., (2010), "Modulation of Amyloid beta Peptide1-42 Cytotoxicity and Aggregation in Vitro by Glucose and Chondroitin Sulfate.", Current Alzheimer research, vol.7, pp. 428-438, ISSN: 1567-2050.
  • Gella, A., (2010), "Immunohistochemical analysis of human brain suggests pathological synergism of Alzheimer's disease and diabetes mellitus.", Neurobiology of disease, vol.37, pp. 67-76, ISSN: 0969-9961.
  • Gella, A., (2008), "Effect of the nucleotides CMP and UMP on exhaustion in exercise rats", Journal of physiology and biochemistry, vol.64, pp. 9-18, ISSN: 1138-7548.
  • Gella, A., (2003), "Preparation of anti-hCG-peroxidase conjugates for enzyme inmunoassays", Clin Chem Lab Med, vol.41 (S1), pp. 395.

Llibres

  • Gella, A., (2011), "Alzheimer's Disease Pathogenesis-Core Concepts, Shifting Paradigms and Therapeutic Targets". INTECH OPEN ACCES PUBLISHER. Janeza Trdine 9, 51000 Rijeka, Croatia. ISBN: 978-953-307-690-4.

Capítols de llibre

  • Gella, A., (2011), "Oxidative Stress in Alzheimer's Disease: Biomarkers & Therapy", Alzheimer's Disease Pathogenesis-Core Concepts, Shifting Paradigms and Therapeutic Targets, pp. 319-344, INTECH OPEN ACCES PUBLISHER. ISBN: 978-953-307-690-4.

Projectes de recerca

Estudio genético en los trastornos generalizados del desarrollo en niños y adolescentes

IP: Gella, A.
Fundación Roviralta
14/07/2011 - 14/07/2012

Efecto del Nucleo CMP Forte en la regeneración neuronal en el sistema nervioso periférico

IP: Gella, A.
Grupo Ferrer
01/02/2011 - 01/02/2012

Evaluation of risk genes for schizophrenia by genetic association studies and mRNA expression in spanish and german cohorts

IP: Gella, A.
Fundación Roviralta
01/01/2010 - 14/07/2011

Estudi metabòlic i genètic en la fatiga crónica i en la resistència a la insulina

IP: Gella, A.
Laboratorios Lety
01/04/2009 - 01/04/2010

Efecto del fármaco Nucleo CMP Forte en células de Schwann y en la encefalomielitis Autoinmune Experimental

IP: Gella, A.
Grupo Ferrer
01/01/2008 - 01/01/2010

Estudio genético sobre la esquizofrenia

IP: Gella, A.
Fundació SENY
01/04/2008 - 01/04/2009

Neuroprotecció de Nucleo CMP Forte en cél.lules nervioses

IP: Gella, A.
Grupo Ferrer
01/01/2007 - 01/01/2008

Asignación de valores a materiales de control y calibradores. Estudios de validación de reactivos e instrumentos.

IP: Gella, A.
BioSystems, S.A
01/01/2007 - 31/12/2007

Estudio de la enfermedad de Zellweger

IP: Gella, A.
Fandació Manuela Martinez
01/11/2006 - 01/12/2007

Preparación de conjugados de anticuerpos monoclonales para emplearlos en la elaboración de reactivos de diagnóstico in vitro-2

IP: Gella, A.
BioSystems, S.A
01/03/2006 - 31/12/2006

Activitats

AAE Meeting

Presentació de comunicació "The biocompatibility, Setting time, Radiopacity and Calcium Release of a New experimental cement", 2011.

Congreso de la Sociedad Española de Neurociencia

Presentació de poster "Housekeeping gene validation for RT-PCR normalization in rat Schwannoma cell line treated with Nucleo CMP Forte", .

International Conference on Alzheimer's Disease

Presentació de poster "Immunochemical Analysis of Advanced Glycation Endproducts and Amyloid in
Alzheimer's disease and Diabetic post-mortem Brain Tissue", .

IFCC-FESCC European Congress of Clinical Chemistry and Laboratory Medicine

Presentació de poster "Development of an ELISA of hCG in human serum using WHO Reference Reagents", .

Link Colloquium (UIC-Università Campus Biomedico di Roma)

Presentació de comunicació "Research in Neurosciences", .

Simposi de Neurobiologia Experimental

Presentació de poster "Genotype delimitation of autism and schizophrenic spectrum disorders", .

World Congress of Biological Psychiatry

Presentació de poster "Copper binding effect on amyloid peptide aggregation in Alzheimer's disease", .

Congreso de la Sociedad Española de Neurociencia

Presentació de poster "Differential protein expression in nucleotide-induced signalling on Schwannoma cell line", .

Congreso de la Sociedad Española de Bioquímica y Biologia Molecular

Presentació de poster "Induction of cell-cell adhesive contacts in Schwannoma cell line by nucleotides", .

Jornada de Recerca en Salut Mental

Presentació de comunicació "Estudi de lèxpressió gènica del BDNF en l'espectre autista i esquizofrènic", .